منابع مشابه
Biologists who count*
The importance of mathematics in biology is a matter of perennial debate. The squabbles of early 20th century geneticists on the value of mathematics to the study of evolution have recently been revisited in Journal of Biology [1], and the 21st century has seen an explosion of information from various -omics and imaging techniques that has provided fresh impetus to the arguments urging the need...
متن کاملWhy Biologists Can’t Count: An Overview of the Gene- Finding Problem
Five years after draft assemblies of the human genome became available the number of genes it contains remains uncertain. Parallel approaches yield divergent estimates of the total gene number, and it is not yet clear how to rationalize this variability. To illustrate the challenges involved in identifying and counting genes, I overview three major a p p r o a c h e s : s e q u e n c e a n a l ...
متن کاملSystems Biology for Biologists
Do you avoid papers thick with mathematical details and unfamiliar statistical analyses? If so, this article is for you! Systems biology, at its core, is not a set of computational and mathematical techniques; these are merely tools, incredibly useful, but secondary. The heart of systems biology is simple: explaining how a system works requires an integrated outlook. For any phenotype—molecular...
متن کاملSociety of Systematic Biologists
-A well-known approach to inferring phylogenies involves finding a phylogeny with the largest number of characters that are perfectly compatible with it. Variations of this problem depend on whether characters are: cladistic (rooted) or qualitative (unrooted); binary (two states) or unconstrained (more than one state). The computational cost of known algorithms that guarantee solutions to these...
متن کاملSociety of Systematic Biologists
Croizat, L., G. Nelson, and D. E. Rosen (Department of Ichthyology, The American Museum of Natural History, New York, New York 10024) 1974. Centers of origin and related concepts. Syst. Zool. 23:265-287.-The concept of center of origin in the Darwinian sense is often accepted and used as if it were a conceptual model necessary and fundamental to historical zoogeographical analysis. But in certa...
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ژورنال
عنوان ژورنال: Journal of Biology
سال: 2009
ISSN: 1475-4924
DOI: 10.1186/jbiol146